Publications

Barbee, K.D.; Hsiao, A.P.; Heller, M.J.; Huang, X. Electric Field Directed Assembly of High-Density Microbead Arrays. Lab on a Chip (2009) DOI: 10.1039/B912876J (ABSTRACT)

Fuller, C.W., Middendorf, L.M., Benner S.A., Church, G.M., Huang, X., Nelson, J.R., Schloss, J.R., Schwartz, D.C., Vezenov, D.V. Sequencing by Synthesis. Submitted

Joneja, A.; Huang, X. A Device for Automated Hydrodynamic Shearing of Genomic DNA. BioTechniques (2009) Jun; 46 (7) 553-556. (ABSTRACT)

Chen, Y.-J.; Huang, X. DNA Sequencing by Denaturation: Principles and Thermodynamic Simulations. Analytical Biochemistry (2009) Jan 1; 384 (1) 170-179. (ABSTRACT)

Branton, D. et al. The Potential and Challenges of Nanopore Sequencing. Nature Biotechnology (2008) Oct 9; 26 (10) 1146-53. (ABSTRACT)

Huang, X. (2008) Genomes, Genomic Technologies and Medicine. In Chien, S.; Chen, P.C.Y.; Fung, Y.C. (Eds.) An Introductory Text to Bioengineering (Advanced Series in Biomechanics) (2nd ed.). Hackensack: World Scientific Publishing.

Barbee, K.D.; Huang, X. Magnetic Assembly of High-Density DNA Arrays for Genomics Analyses. Analytical Chemistry (2008) Mar 15; 80 (6) 2149-54. (ABSTRACT)

Bulyk, M.L.; Huang, X.; Choo, Y.; Church, G.M. Exploring the DNA-Binding Specificities of Zinc Fingers with DNA Microarrays. Proc. Natl. Acad. Sci. U.S.A. (2001) Jun 12; 98 (13). (ABSTRACT)

Zhong, X.; Lizardi, P.M.; Huang, X.; Bray-Ward, P.; Ward, D.C. Visualization of Oligonucleotide Probes and Point Mutations in Interphase Nuclei and DNA Fibers Using Rolling Circle DNA Amplification. Proc. Natl. Acad. Sci. U.S.A. (2001) 98:3940-3945. (ABSTRACT)

Ozcan,T., Burki, N., Parkash, V., Huang, X., Pejovic, T., Mahoney, M.J., Mari, G. and Ward, D.C. Cytogenetical Diagnosis in Paraffin-embedded Fetoplacental Tissue Using Comparative Genomic Hybridization. Prenatal Diagnosis. (2000) 20 (1): 41-44. (ABSTRACT)

Lizardi, P.M.; Huang, X.; Zhu, Z.; Bray-Ward, P.; Thomas, D.C.; Ward, D.C. Mutation detection and single molecule counting using isothermal rolling circle amplification. Nature Genetics (1998) 19: 225-232. (ABSTRACT)

Huang, X.; Boxer, S.G. Discovery of New Ligand Binding Pathways in Myoglobin by Random Mutagenesis. Nature Structural Biology (1994) 1 (4): 226-229. (ABSTRACT)

Huang, X. Probing Ligand Binding Dynamics and Folding of Myoglobin Using a Random Library of Myoglobin Mutants with Single Amino Acid Mutations, Ph.D. Thesis Stanford University (1997).

Patents

Huang, X.; Roller, E. Genome Sequencing by Mostly Natural DNA Synthesis. Application No. (2009).

Huang, X. Methods and Systems for Direct Real-Time Sequencing of Single DNA Molecules. Application No. 61/121,809 (2008).

Barbee, K.D.; Huang, X. Methods and Devices for Biomolecular Arrays. Application No. 60/887,244 (2007).

Lizardi, P.M.; Huang, X. Single Molecule Analysis Target-Mediated Ligation of Bipartite Primers. Patent No. 6,316,229 (2001) (Full PDF)

Funding

Genome Sequencing by Natural DNA Synthesis on Amplified Clones (NIH/NHGRI R01 HG004804) (ABSTRACT)

Genome Sequencing by Ligation Using Nano-Arrays of Single DNA Molecules (NIH/NHGRI R21 R21HG04130) (ABSTRACT)

Career Award (NSF BES-0547193)

Massively Parallel Cloning and Sequencing of DNA (NIH/HNGRI R21 R21HG03587) (ABSTRACT)

Website design and maintenance by Kristopher D. Barbee

Genomics and Systems Biotechnology Laboratory

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